Free radicals are intermediates in many normal and necessary metabolic reactions. Thus, all oxygen-using organisms have had to evolve defensive mechanisms against free radicals: The enzymes catalase and peroxidase break down hydrogen peroxide and other peroxides, superoxide dismutase (called SOD) controls the superoxide free radical, and glutathione peroxidase also controls peroxides. Antioxidants such as vitamins […]
Read more Our Subversive Free Radicals III
- acid hydrolases, air pollution, antioxidants, bacteria, bioavailability, brain, cancer, catalase, Cross-linking, enzymes, free radicals, genetic defects, glutathione peroxidase, heart, hyaluronate, hydrogen peroxide, liver, lysosomes, malonaldehyde, maximum lifespan potential, metabolic reactions, mlp, mutagen, oxidation, peroxidase, peroxidized fats, progeria, radiodurans, red blood cells, rheumatoid arthritis, selenium, SOD, superoxide dimutase, superoxide dismutase, superoxide radicals, vitamin E
where: R is an organic molecule ROOH is an organic peroxide R:R are two organic molecules which have been cross-linked to- gether Oz is oxygen Cu is copper, Fe is iron *is the unpaired electron H is a hydrogen atom HO* is a superoxide free radical RO,* and R* are organic free radicals Note that […]
Read more Our Subversive Free Radicals IV
- aging, amino acid, antioxidants, artery walls, atherosclerotic plaque cells, BHA, BHT, cancer, coronary thrombosis, cysteine, Dr. Wilfred E. Shute, ethoxyquin, free radicals, genetic mutations, glutathione, heart attack, L-Dopa, Lasker research award, peroxidized fats, PGI, phenolic amino acid, platelet, prostacyclin, prostacyclin synthetase, selenium, stroke, sulfur, thromboxane, tyrosine, vitamin A, vitamin c, vitamin E
Selenium, a mineral, is an important trace element in immune system function. It has been found in experimental animals to act as an anti-carcinogen and anti-mutagen (can prevent DNA mutations—undesired alterations of your DNA master blueprint in the presence of some mutagenic agents). Selenium is an essential part of your enzyme called glutathione peroxidase, which […]
Read more Aging and the Immune System III
- Allan L. Goldstein, anti-carcinogen, anti-mutagen, aorta, bacteria, bromelain, cholesterol, DNA, Dr. Takashi Makiodan, enzymes, fibroblasts, glutathione peroxidase, high-cholesterol diet, hydrogen peroxide, immune system, immune system suppressants, interferon, lymphocytes, oxidation, papain, peroxides, selenium, stem cells, T-cells, thymosin, thymus gland, trypsin, vitamin A, vitamin c, vitamin E, white blood cells
… just as the pigment of the hair is destroyed by phagocytes, so also the atrophy of other organs of the body, in old age, is very frequently due to the action of devouring cells which I have called macrophages. —Elie Metchnikoff, The Prolongation of Life (1908) Instead of preventing diseases only by protecting the […]
Read more Aging and the Immune System I
- aging, amino acid, antibodies, arthritis, atherosclerosis, atherosclerotic plaque cells, autoimmune disease, bacteria, bone marrow, cancer, chromosome, cysteine, ducts, Elie Metchnikoff, free radicals, immune system, influenza, interferon, Life extension, lymph nodes, microbes, microphages, nerve cells, polypeptides, proteins, selenium, spleen, T-cells, thymus gland, virus, vitamin A, vitamin c, vitamin E, white blood cells, X chromosome, Y chromosome, zinc
Most vitamins are soluble in either the watery or the fatty tissues of our bodies, but not in both. Vitamins C and B are water soluble; vitamins A, E, D, and K are fat soluble. Both types of vitamins are necessary for health and long life. We have different storage capacities for different vitamins. For […]
Read more Molecules of Life and Life Extension: An Introduction to the Cast II
- adenosine triphosphate, amino acid, anti-aging enzyme, ATP, Carbohydrates, citric acid cycle, copper, energy, enzymes, fat soluble vitamin, glutathione peroxidase, iron, manganese, minerals, PABA, peptides, proteins, selenium, superoxide dismutase, vitamin b, vitamin B12, vitamin c, vitamin D, vitamin E, Vitamin K, water soluble vitamin, zinc