The Blind Men and the Elephant; or, The Many Mechanisms of Aging III

Progress in control of aging was very slow in the early years of gerontological research, a few decades ago. Research ers did not understand why various procedures (such as dietary restriction in young rats) or substances (like RNA) prolonged animal life spans. The discoveries of several mechanisms of aging have vastly accelerated the rate of […]

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Prolonging Life in the Laboratory; or, Why Animal Experiments Are Relevant to Humans

The most beautiful thing we can experience is the mysterious. It is the source of all true art and all science. He to whom this emotion is a stranger, who can no longer pause to wonder and stand rapt in awe, is as good as dead: his eyes are closed. —Albert Einstein Most biological experiments […]

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The Synthetic Versus Natural Controversy II

“A vitamin C is a vitamin C is a vitamin C.” A synthetic (made by a chemical factory) molecule of vitamin C is exactly the same as a natural (made by a plant’s biochemical factory) molecule of vitamin C. It is argued that there may be nutritional cofactors (some possibly unidentified) accompanying natural vitamins. It […]

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The Synthetic Versus Natural Controversy I

You say nothing’s right but natural things … you fool. Poison oak is a natural plant—why don’t you put some in your food? I don’t care if there’s chemicals in it, as long as my lettuce is crisp! Preservatives might just be preserving you,I think that’s something you missed! —”Eat Starch Mom,” lyrics by Grace […]

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How Do You Know Who’s Right? III

In scientifically sound studies, researchers allow for variations by using a device called controls. Controls are experimental subjects who are exposed to exactly the same conditions as the test subjects—those receiving treatment— except that they do not receive the treatment being tested. Ideally, this should be the only variable between control and experimental groups. Controls […]

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How Do You Know Who’s Right? II

Successful prediction by a hypothesis is considered strong evidence in support of its validity. Thus, tests for various logical consequences of a hypothesis are devised. For example, Einstein’s general theory of relativity required that a ray of light passing a massive object (such as a star) would be bent by the gravitational field of that […]

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How Do You Know Who’s Right? I

Don’t ever confuse hard work with hard thinking. —James Watson, Nobel laureate One famous doctor says, “Eat mostly starches and little fats or protein.” Another famous doctor claims, with equal vigor, “Eat mostly protein, little starches or fats.” A third doctor argues against both of them by citing a research study indicating that Eskimos on […]

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Some Social Consequences of Life Extension

Death, be not proud, though some have called thee Mighty and dreadful; for thou art not so…. And Death shall be no more: Death, thou shalt die! —John Donne (1573-1631) The consequences to ourselves and our society of greatly extended human life span are sure to be far reaching. An extended life span does not […]

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Common Fears About Life Extension II

In fact, in some experiments the animals are vigorous and, to all outward appearances, youthful until just a few hours before death, when they succumb suddenly. In our society, there may be a problem in those organizations where seniority is very important, such as corporations, unions, philanthropic organizations, and governments, allowing officeholders to hold power […]

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