interfere with PAH activation and/or binding to DNA, thereby reducing the amount of DNA damage done. Rate and accuracy of repair of ultraviolet (UV) light damage to DNA in seven mammalian species’ cultured fibroblasts correlates with maximum species life span. Repair of damage to DNA plays a vital role in retarding aging, although the importance […]
Read more Factors Which Correlate with Natural Longevity III
… Spontaneous mutations, cancer, and aging can be looked upon as a result of continuous “internal radiation” while these same processes produced by external radiation are largely the result of an increment in the amount of total “radiation” to which the organism is exposed. —Dr. Denham Harman, originator of the free radical theory of aging […]
As mentioned earlier, Dr. W. Donner Denckla thinks he has discovered a death clock in the pituitary gland of the brain. If he removes this gland from mice and supplies them with the pituitary’s growth hormone and thyroid hormone (which would normally be produced and released in response to pituitary hormonal messages), the animals live […]
Free radicals are intermediates in many normal and necessary metabolic reactions. Thus, all oxygen-using organisms have had to evolve defensive mechanisms against free radicals: The enzymes catalase and peroxidase break down hydrogen peroxide and other peroxides, superoxide dismutase (called SOD) controls the superoxide free radical, and glutathione peroxidase also controls peroxides. Antioxidants such as vitamins […]
Most vitamins are soluble in either the watery or the fatty tissues of our bodies, but not in both. Vitamins C and B are water soluble; vitamins A, E, D, and K are fat soluble. Both types of vitamins are necessary for health and long life. We have different storage capacities for different vitamins. For […]
Read more Molecules of Life and Life Extension: An Introduction to the Cast II