… Spontaneous mutations, cancer, and aging can be looked upon as a result of continuous “internal radiation” while these same processes produced by external radiation are largely the result of an increment in the amount of total “radiation” to which the organism is exposed. —Dr. Denham Harman, originator of the free radical theory of aging […]
Read more Our Subversive Free Radicals I
- atherosclerosis, cancer, DNA, enzymes, fats, free radicals, glutathione peroxidase, hydrogen peroxide, immune system, molecules, mutations, nucleic acid, oxidation, radiation, RNA, SOD, superoxide dismutase, vitamin c, vitamin E
Empiricism may serve to accumulate facts, but it will never build science. The experimenter who does not know what he is looking for will not understand what he finds. —Claude Bernard, 1813-1878 When your skin wrinkles, or arteries or bread hardens, or rubber becomes brittle, or old Jell-O® stiffens, we are seeing examples of the […]
Read more Cross-linked Molecules and Aging in Skin, Arteries, and Other Tissues I
- acetaldehyde, alcohol, amino acid, arteries, atherosclerosis, cancer, cells, Cross-linking, cysteine, DNA, eggs, esters, flexibility, hemorrhage, liver, metabolism, molecules, nutrients, PABA, proteins, rats, RNA, sunlight, tissues, tobacco, ultraviolet light, vitamin b, vitamin B1, vitamin c, wrinkles
… just as the pigment of the hair is destroyed by phagocytes, so also the atrophy of other organs of the body, in old age, is very frequently due to the action of devouring cells which I have called macrophages. —Elie Metchnikoff, The Prolongation of Life (1908) Instead of preventing diseases only by protecting the […]
Read more Aging and the Immune System I
- aging, amino acid, antibodies, arthritis, atherosclerosis, atherosclerotic plaque cells, autoimmune disease, bacteria, bone marrow, cancer, chromosome, cysteine, ducts, Elie Metchnikoff, free radicals, immune system, influenza, interferon, Life extension, lymph nodes, microbes, microphages, nerve cells, polypeptides, proteins, selenium, spleen, T-cells, thymus gland, virus, vitamin A, vitamin c, vitamin E, white blood cells, X chromosome, Y chromosome, zinc