interfere with PAH activation and/or binding to DNA, thereby reducing the amount of DNA damage done. Rate and accuracy of repair of ultraviolet (UV) light damage to DNA in seven mammalian species’ cultured fibroblasts correlates with maximum species life span. Repair of damage to DNA plays a vital role in retarding aging, although the importance […]
Read more Factors Which Correlate with Natural Longevity III
- acetaldehyde, air pollution, cancer, DNA, Dr. R. B. Setlow, Dr. Ronald W. Hart, enzyme, fibroblasts, free radicals, genetic disease, globulin, glutathione peroxidase, hemoglobin, life span, nitrogen oxide, ozone, PAH, peroxyacetylnitrile, progeria, skin erythema, SOD, superoxide dismutase, ultraviolet light, UV, Xeroderma pigmentosa
Free radicals are intermediates in many normal and necessary metabolic reactions. Thus, all oxygen-using organisms have had to evolve defensive mechanisms against free radicals: The enzymes catalase and peroxidase break down hydrogen peroxide and other peroxides, superoxide dismutase (called SOD) controls the superoxide free radical, and glutathione peroxidase also controls peroxides. Antioxidants such as vitamins […]
Read more Our Subversive Free Radicals III
- acid hydrolases, air pollution, antioxidants, bacteria, bioavailability, brain, cancer, catalase, Cross-linking, enzymes, free radicals, genetic defects, glutathione peroxidase, heart, hyaluronate, hydrogen peroxide, liver, lysosomes, malonaldehyde, maximum lifespan potential, metabolic reactions, mlp, mutagen, oxidation, peroxidase, peroxidized fats, progeria, radiodurans, red blood cells, rheumatoid arthritis, selenium, SOD, superoxide dimutase, superoxide dismutase, superoxide radicals, vitamin E