Let’s think about the effects of aging on OUR APPEARANCE. Under natural conditions, the skin shows age in a variety of unattractive ways, including wrinkling and loss of resiliency, both due to the damage mechanism called crosslinking.
Cross-linking is the process in which proteins are linked together by bonds which prevent them from functioning properly. (This is also what makes your car’s windshield-wiper blades, tires, and rubber hoses become brittle and cracked.) Nutrients can be effectively used to inhibit the progression of this mechanism of aging. The tanning of leather is an example of cross-linking; soft supple skin becomes hard, stiff, inelastic shoe leather. Scientists studying the biology of aging have done considerable work in the understanding of cross-linking and the discovery of compounds which can prevent or reverse it. Effective preventive anti-cross-linkers include cysteine, zinc, selenium, vitamins E, C, B-1, and A, and the antioxidant food additives BHT and BHA.
Some scientists hope to be able to develop an anti-cross-linking agent that can be put on the skin like a cosmetic but which would actually unwrinkle the skin! This might be done with proteolytic enzymes—enzymes which dissolve protein, especially those selective for breaking cross-links. Raw pineapple contains bromelain and raw papaya contains papain, both proteolytic enzymes.
The appearance and condition of SKIN can also be improved quickly with the sodium salt of 2-pyrrolidone-5-carboxylic acid, Na-PCA, the natural humectant (moisturizer) in your skin. As people age, the quantity of Na-PCA decreases, causing the skin to become dry. Old folks typically have about
half the Na-PCA in their skin as youngsters. Excessive washing dries your skin because it carries away your Na-PCA. Na-PCA is an ingredient in some premium quality skin-care cosmetics. People used to believe that the oil in skin was what kept it soft and flexible. However, pieces of hardened skin immersed in oils do not regain flexibility. Immersion in water, however, does increase flexibility. The ability of samples of skin to hold moisture is directly related to their content of Na PCA. A small amount of Na-PCA placed in a bowl and left in the Sahara desert will become a puddle within a few hours because of the water pulled right out of the dry desert air!
How would you like to promptly improve your MENTAL OR-
GANIZATION, your MEMORY, and your LEARNING ABILITY with a simple nutrient available at many health food and drug stores? Choline has, to a certain extent, done this in human studies. MIT students taking 3 grams of choline a day could learn longer lists of words and could remember better. These results are usually noticeable within a few days. Choline bitartrate, the most common type of choline sold in health food stores, can cause diarrhea. If you use choline bitartrate, you may have to start at a low dose and work it up slowly to avoid diarrhea. Choline chloride (also called choline hydrochloride) does not have this side effect.
Choline may have a slight drawback for some people because action by bacteria in the intestinal tract can change it into an unpleasant fishy-smelling substance called trimethylamine. This has not happened to most people we know who are using choline. However, it has been reported (in Wurtman and Wurtman’s Nutrition and the Brain, Raven Press, 1979) that most patients ingesting choline chloride did have this problem. One difference between these patients and people we know who use choline is
that the latter group is also taking other nutrients along with the choline. If a fishy smell is a problem for you, try altering your gut bacteria with yogurt, extra dietary fiber, and vitamin supplements.
Even faster MENTAL IMPROVEMENT can be obtained with the hormone vasopressin, released by the brain’s pituitary gland and also available in a nasal spray (Diapid®, a prescription drug made by Sandoz). In one study, men in their 50s and 60s taking 16 I.U. of Diapid® nasal spray per day had significant improvements in memory and learning and decreased reaction time (the men were faster!). In several cases of accident-induced amnesia, people recovered their memory in only hours to days after using Diapid®. A nurse had suffered amnesia as a result of an automobile accident which covered a period of months, both before and after the accident. Within seconds after using the vasopressin nasal spray, she tsaid that she could feel her mind clearing as if a fog had lifted.
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